Essential AR45 artifact farming guide covering optimal domain priorities, strongbox optimization, and resin efficiency strategies for maximizing 5-star artifact acquisition.
Understanding AR45: The Artifact Farming Milestone
Why AR45 Changes Everything
Here's the thing about AR45 that most guides don't emphasize enough – it's not just an improvement, it's a complete paradigm shift. Domain Level III doesn't just unlock better rewards; it guarantees one 5-star artifact per 20-Resin run. We're talking about a 71% efficiency jump from those frustrating pre-AR45 runs where you'd get maybe 30-50% drop rates if RNG smiled on you.

Let me put this in perspective: your weekly resin regeneration of 1,260 suddenly yields a minimum of 63 guaranteed 5-star artifacts. Before AR45? You were lucky to see 22-32 pieces. That's not just better – that's game-changing.
Each domain run averages 1.07 five-star artifacts, which doubles to 2.14 with Condensed Resin (and honestly, if you're not using Condensed Resin at this point, we need to talk). Five-star artifacts pump out 3,780 EXP compared to four-star pieces' measly 2,520, meaning you'll achieve functional sets 40-60% faster.
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The Resin Strategy Revolution
Pre-AR45, your resin was scattered everywhere. Forty on Normal Bosses, twenty on talent books, twenty on weapon materials, twenty on Ley Lines, thirty on Weekly Bosses. Sound familiar?
Post-AR45 changes everything. Enter the 80/20 rule: 144 daily Resin (that's 80%) goes straight to artifact domains, with just 36 Resin for everything else. This focused approach isn't just efficient – it's the difference between having mediocre artifacts in six months versus having solid builds in two.
2025 Artifact Domain Tier List & Priority Ranking
S-Tier: The Domains You Live In
Momiji-Dyed Court is where dreams come true.

Emblem of Severed Fate converts 75% of your ER into Burst DMG at a 0.25% rate per 1% ER – which means characters running 200% ER get a whopping 50% Burst DMG bonus. We're talking Raiden, Xiangling, Xingqiu, Yelan – basically half your roster benefits from this set.
Shimenawa's Reminiscence comes along for the ride, making this domain absurdly efficient.
Denouement of Sin might have a pretentious name, but it delivers. Marechaussee Hunter gives you 36% CRIT Rate through HP fluctuation (that's essentially a perfect CRIT Rate Circlet), while Golden Troupe provides 70% off-field Skill DMG bonus. Both sets absolutely dominate the 2025 meta.
Spire of Solitary Enlightenment rounds out the S-tier with Deepwood Memories offering 30% Dendro RES reduction (multiplicative, not additive – huge difference) and Gilded Dreams providing 14% ATK per same-element team member or 50 EM per different element. Essential if you're running any Dendro reaction teams.
A-Tier: Situational But Strong
Peak of Vindagnyr earns its spot purely because Blizzard Strayer is broken for Freeze teams. Forty percent CRIT Rate against Frozen enemies? Yes, please. Heart of Depth tags along with 30% Normal/Charged Attack DMG for Hydro DPS characters.
Hidden Palace of Zhou Formula presents an interesting case. Crimson Witch remains best-in-slot for Pyro DPS with 37.5% Pyro DMG and 15% reaction damage, but it's paired with the utterly niche Lavawalker. Honestly? Just use the Strongbox for Crimson Witch instead.
Clear Pool and Mountain Cavern – look, VV's 40% RES shred is irreplaceable for Anemo supports, but farming this domain is painful because of Maiden Beloved. Use Strongbox exclusively for VV. Trust me on this one.
Strongbox System: Your Secret Weapon
How This Game-Changer Works
The Strongbox lets you trade 3 unwanted 5-star artifacts for 1 targeted piece. That 3:1 ratio costs you 11,340 EXP, but here's the kicker – you get a 34% chance for 4-substat artifacts versus domains' 20% rate. You can exchange up to 39 artifacts for 13 outputs per session.

Those elusive Elemental DMG Goblets? Still 5% drop rates. ER/EM Sands maintain their 10% rates each. The RNG doesn't change, but your targeting improves dramatically.
Strongbox Priority List
SS-Tier Must-Haves: Viridescent Venerer (because farming it directly is torture), Emblem of Severed Fate (universal Burst support), Tenacity of the Millelith (20% ATK team buff that everyone needs).
S-Tier Targets: Noblesse Oblige (another universal team buff), Crimson Witch (Pyro DPS best-in-slot), Wanderer's Troupe (exclusive to bosses and Strongbox, essential for Melt Ganyu builds).
Pro tip: Target sets from inefficient domains while farming efficient ones. Always lock your Elemental DMG Goblets, CRIT Rate/DMG Circlets, and ER/EM Sands before trading. Keep anything with 3+ desirable substats as potential off-pieces.
Meta Artifact Sets: What Actually Matters in 2025
The Universal Champions
Emblem of Severed Fate continues its dominance with that sweet 75% ER-to-Burst DMG conversion

for characters running 160-220% ER. It's not just good – it's broken.
Marechaussee Hunter revolutionized the game by providing 36% CRIT Rate through HP fluctuation. That's equivalent to a perfect CRIT Rate Circlet just from your 4-piece bonus.
Golden Troupe changed everything for off-field DPS with its 70% Skill DMG bonus for characters not on-field. Fischl mains, this one's for you.
Character-Specific Priorities
For DPS characters, you're looking at Level 80/90 minimum, weapon at 90, talents at 8/8/8. CRIT ratio should hit that golden 1:2 (75% Rate, 150% DMG is optimal). Standard setup: ATK% Sands, Elemental DMG% Goblet, CRIT Rate/DMG% Circlet.
Support characters can chill at Level 70/80, but get that key talent to level 8. ER requirements vary wildly – DPS characters need 110-130%, supports want 180-220%. For reaction supports, you're chasing 800+ EM for Hyperbloom teams.
Anemo supports get special treatment because VV's 40% multiplicative RES shred is irreplaceable. Prioritize EM main stats (good luck with that 2.5% drop rate on EM Goblet/Circlet), ER substats, and CRIT for damage dealers.
Domain Farming Teams That Actually Work
F2P Compositions That Don't Suck
For Emblem Domain, try Klee + Xiangling + Bennett + Flex for Pyro advantage against those annoying Electro enemies. No Klee? Diluc + Xiangling + Barbara + any Anemo grouper works fine. Focus the Electro Hypostasis first – it's the real threat.

Husk Domain loves Geo teams. Noelle + Gorou + Geo Traveler + Flex absolutely destroys with Geo advantage. Physical teams (Razor/Eula) provide consistent damage against the varied enemy types too.
Well-optimized teams achieve 30-45 second clears through proper element matching. The famous Rational team (Raiden + Xiangling + Bennett + Xingqiu) can sub-30 second the Emblem domain with proper investment.
Resin Management: The 80/20 Rule
Daily Allocation Strategy
Stick to the 80/20 rule religiously: 144 daily Resin for artifact domains, 36 Resin for everything else. Your daily regeneration gives you 180 Resin over 24 hours (8 minutes per point), and that 200 cap provides a nice 20-point buffer for timing.
Weekly, that 1,260 Resin yields minimum 63 five-star artifacts, enabling functional builds for 3-4 characters monthly. That's sustainable progression.
Condensed Resin: Use It or Lose It
Condensed Resin doubles rewards for 40 Resin while halving your time investment. Craft with 40 Original Resin + 1 Crystal Core + 100 Mora, store up to 5. Requires Liyue Reputation Level 3, but works on all domains except bosses.
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Refresh Value Analysis
Each Fragile Resin (60 Original) yields 3.21 five-star artifacts post-AR45. Allocate 80% to domains, reserve 10-20% for events. Primogem refreshes start at 50 for the first daily (60 Resin), escalating to 100, then 200. Stockpile 150-200 Fragile Resin for major events.
Weekly Bosses vs Domain Farming
The Weekly Boss Calculation
Your first three weekly bosses cost 30 Resin each (90 total), yielding 2.2-2.39 talent materials, 1.24 five-star artifacts, 0.325 Dream Solvent, and 0.12 weapon billets on average. Prioritize Tier 1 bosses (Azhdaha, Signora, Raiden) for the most valuable materials.
Optimal balance: 90 Resin for weekly discounted bosses, 1,170 Resin for domains (7:93 ratio). Complete them Monday-Thursday for discount timing. Plan in 6-month cycles focusing on 2-3 core teams.
Artifact Enhancement & Inventory Sanity
Fodder Farming Routes
Daily investigation routes provide 60,000 artifact EXP – that's equivalent to 80 Resin worth of fodder. Complete Liyue/Mondstadt circuits in 15-20 minutes. Use +0 artifacts for 100% EXP efficiency. Level to +16 for evaluation using just 60% of the EXP requirements to reveal 80% of the potential.
Storage Without Going Insane
Lock valuable artifacts immediately – seriously, do it the moment you see them. Apply the 3-stat rule: preserve anything with 3+ desirable substats (CRIT Rate/DMG, ATK%, ER) regardless of set. Maintain one copy per main stat/set combination. Always keep Elemental DMG Goblets, CRIT Rate/DMG Circlets, and ER/EM Sands as potential off-pieces.
Batch your Strongbox trades in 39-piece increments when approaching that 1,800 inventory limit. Use the CRIT Value formula (CRIT Rate × 2 + CRIT DMG): 31-40 is good, 41-50 is excellent, 51-60 is perfect. Remember, +20 artifacts require 270,000 Mora plus all that fodder.
Common Mistakes & Hard-Learned Lessons
The Biggest Farming Blunders
Pre-AR45 Intensive Farming: This 36-58% efficiency loss compounds over time and causes serious World Level 5-6 struggles. Focus on ascension materials, talents, and weapons until you hit that guaranteed 5-star threshold.
Perfectionism Paralysis: I've seen players spend months pursuing perfect artifacts while their teams struggle with basic content. Target correct main stats plus 2-3 relevant substats for 80-90% performance using 40-60% less time.
Ignoring Strongbox Efficiency: Direct farming inefficient domains is just throwing Resin away. Convert unwanted pieces for VV, Crimson Witch, and other valuable sets from terrible domains.
Expert-Level Optimization
Hybrid Methodology: Spend 60-70% of your time in efficient domains, convert 30-40% of unwanted pieces via Strongbox. This enables simultaneous progression on 3+ sets.
Conditional Enhancement: Level to +16 for evaluation before committing to +20. This preserves 40% of costs while revealing 80% of the artifact's potential.
Inventory Cycling: Maintain 1,500-1,600 pieces with weekly Strongbox trading to prevent overflow while ensuring you always have exchange materials ready.
Focus on universal sets (Emblem, Marechaussee Hunter, Golden Troupe) for lasting value. Plan in 6-12 month cycles rather than chasing immediate perfection – it's more sustainable and honestly more fun.
FAQ
What makes AR45 so important for artifact farming? AR45 guarantees one 5-star artifact per 20-Resin run versus the 30-50% RNG nightmare of pre-AR45 rates. That's a 71% efficiency improvement that changes everything.
Which domains should I prioritize first? Start with Momiji-Dyed Court for Emblem/Shimenawa, then hit Denouement of Sin for Marechaussee Hunter/Golden Troupe, followed by Spire of Solitary Enlightenment for Dendro sets.
How does Strongbox work and when should I use it? Trade 3 unwanted 5-star artifacts for 1 targeted piece. Use it for sets from inefficient domains like VV, Crimson Witch, and Tenacity while farming efficient domains daily.
Should I use Condensed Resin for artifacts? Always. It doubles rewards while halving time. Maintain maximum 5 pieces and craft during low-activity periods.
How much daily Resin should go to artifacts? Follow the 80/20 rule: 144 Resin (80%) for artifacts, 36 Resin (20%) for secondary priorities. This maximizes progression while maintaining character development.
What's the biggest AR45 mistake? Chasing perfect artifacts instead of building functional sets. Target correct main stats plus 2-3 relevant substats for 80-90% performance using 60% less time and stress.